Article by Leaf Science
Marijuana is often associated with the well-known psychoactive component THC. CBD is a non-psychoactive compound in marijuana that is known for its many medical benefits.
Current research suggests that CBD may be able to help treat symptoms of Parkinson’s disease, such as movement and sleep problems.
Here, we examine how CBD can help patients with Parkinson’s disease, and how it may work alongside THC.
Can CBD Treat Parkinson’s Disease?
Research on treating Parkinson’s disease with CBD is still in its early stages. However, recent evidence has emerged suggesting CBD can benefit patients living with the disease.
CBD has been shown to have neuroprotective and antipsychotic effects. It may also improve sleep disturbances and quality of life in Parkinson’s patients.
A 2005 study published in the journal Neurobiology of Disease was one of the earliest studies to show that CBD may help Parkinson’s disease. The researchers found that CBD had neuroprotective effects in animal models of Parkinson’s.
Since then, more research on CBD and Parkinson’s has emerged. Overall, studies indicate that CBD may be able to improve many aspects of Parkinson’s disease, including movement impairments, psychosis, sleep disturbances, and quality of life.
Effects of CBD on Parkinson’s Disease
One of the most characteristic symptoms of Parkinson’s disease is dystonia, or disordered movement. Movement symptoms result from a loss of dopamine-producing cells in the brain.
A 2017 study determined CBD might help the movement impairments in Parkinson’s by interacting with a receptor known as GPR6.
The researchers found that CBD blocks this receptor, causing dopamine levels to increase. They believe that some of the effects of CBD observed in patients with Parkinson’s can be explained by its action on this receptor.
A 2005 study found that CBD has neuroprotective effects on dopamine-producing cells in mice. It was suggested that these effects may be due to the antioxidant or anti-inflammatory properties of CBD.
Researchers exposed the animals to a chemical toxin that kills dopamine-producing brain cells, and then administered CBD. They found that CBD reduced the extent of the damage.